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Why Palms of Hands Itch: A Clinical Guide to Diagnosis and Management in 2026

"Itching of the palms, clinically referred to as palmar pruritus, is a common dermatological complaint that can stem from anything from transient environmental contact to systemic metabolic conditions. As of 2026, medical practitioners utilize refined diagnostic frameworks to distinguish between benign skin irritation and underlying pathologies that require specialized intervention. This guide provides an evidence-based overview of the physiological, environmental, and systemic triggers for palmar pruritus, aligned with current diagnostic standards. Physiological Drivers and Differential Diagnosis of Palmar Pruritus Palmar skin is unique in it..."

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